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The cause of the FQAD is multifactorial and is the result of complex interactions including mitochondrial DNA (mtDNA) mutation, respiratory chain dysfunction and increased oxidative stress from mitochondrial damage [36]

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The agency's enforcement posture toward peptide research compounds has intensified since 2020, with multiple warning letters issued to suppliers marketing unapproved peptides directly to consumers

Bai L, Ma H, Huang Y, Luo Y

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